The Cape Town Declaration on Gender Incongruence of Childhood (GIC) was publicly released, requesting the removal of the World Health Organization’s (WHO) International Classification of Diseases (ICD) diagnoses that pathologise gender diversity in children and youth. The Declaration was issued by a working group of 40 delegates from 11 countries who met on 2 June 2014 at the 2nd Trans Health, Research and Advocacy Conference in Cape Town, and was submitted to the World Professional Association for Trans Health. The Declaration was also included in the submission to the United Nations (UN) 3rd cycle Universal Periodic Review.