Iranti was founded by Jabulani Chen Perreira in 2012. Jabulani, the organisation’s leadership, and the entire team is composed of trans, lesbian, and intersex persons. Iranti is an African regional organisation that involves media and documentation in its advocacy.

Intersex Society South Africa (ISSA), founded and run by Sally Gross until her passing, underwent a “make-over” and is now housed at Iranti. Other trans and intersex-specific programmes include documenting and advocacy regarding trans health and access to medical care, and advocacy around the World Health Organization (WHO)’s ICD-10.